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Apr 27, 2012 · In this issue of Cell, Rajasethupathy et al. report a surprising role for piRNAs, previously thought to act mainly in the animal germline to silence transposons, in transcriptional regulation of plasticity-related genes in the central nervous system of the sea slug Aplysia californica.
A new study by Dr. Ran Elkon, Edmond J. Safra faculty fellow (Medicine) and colleagues, identifies a frequent technical bias in RNA-seq data.. Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified.
BibTeX @MISC{Elkon08removalof, author = {Ran Elkon and Reuven Agami}, title = {Removal of AU Bias from Microarray mRNA Expression Data Enhances Computational Identification of Active}, year = {2008}}
Michal Gavish-Izakson, Bhagya Bhavana Velpula, Ran Elkon, Rosario Prados-Carvajal, Georgina D Barnabas, Alejandro Pineiro Ugalde, Reuven Agami, Tamar Geiger, Pablo Huertas, Yael Ziv, Yosef Shiloh. Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.
Sep 15, 2018 · كلمات مهرجان رب الكون ميزنا بميزه | حمو بيكا mhrgan Rab elkon maizna b meza hamo beka Magnon EL Media - مجنون الميديا ...
2018-11-06 13:44:03. The Elkton Police Department is happy to announce that our very own CPL Todd Finch was recognized this past Friday Night at the Cecil County First Responders Appreciation Dinner sponsored by the Cecil County Chamber of Commerce.
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Gozde Korkmaz, Zohar Manber, Rui Lopes, Stefan Prekovic, Karianne Schuurman, Yongsoo Kim, Hans Teunissen, Koen Flach, Elzo de Wit, Giorgio G Galli, Wilbert Zwart, Ran Elkon, Reuven Agami, A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation, Nucleic Acids Research, Volume 47, Issue 18, 10 October 2019, Pages 9557–9572 ...
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Hertzano’s group, in collaboration with Ran Elkon, PhD, Senior Lecturer, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine in Tel Aviv, Israel took a bioinformatics and functional genomics approach to discover a gene critical for the regulation of genes involved in outer hair cell development. Bowl’s group ...
Dec 18, 2019 · The study was conducted by Dr. Shir Mandelbaum, Dr. Zohar Manber, Dr. Orna Elroy-Stein and Dr. Ran Elkon at TAU's Sackler Faculty of Medicine and George S. Wise Faculty of Life Sciences and was ...
The development of powerful experimental strategies for functional genomics and accompanying computational tools has brought major advances in the delineation of transcriptional networks in organisms ranging from yeast to human.
Analysis of numerous RNA-seq datasets reveals a recurrent sample-specific length bias that causes frequent false positive calls by gene-set enrichment analyses, leading to functional misinterpretation of the data. Its removal requires methods that allow the integration of gene length as sample-specific covariate.
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Ran Elkon is a Faculty Fellow of the Edmond J. Safra Center for Bioinformatics at Tel Aviv University. Web Design & Development by PixelCasa ...
Oct 02, 2018 · FigoEld5lawe مهرجان " رب الكون ميزنا بميزه " حمو بيكا - علي قدوره - نور التوت - توزيع فيجو الدخلاوي 2019
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Cover: Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) relies on on-off duty cycles of photoswitchable dyes to provide quantitative thresholds between true signals, emitted from an RNA copy (blue) hybridized with multiple oligonucleotide probes (yellow), and background noise.
Jun 27, 2018 · Neuroadaptations in the brain reward system caused by excessive alcohol intake, lead to drinking escalation and alcohol use disorder phenotypes. Activity-dependent neuroprotective protein (ADNP ...
Jan 11, 2016 · CRISPR-Cas9 is used for both enrichment and dropout screens of functional enhancers in human cells. Systematic identification of noncoding regulatory elements has, to date, mainly relied on large ...
Apr 13, 2005 · The four major expression patterns in the damage-induced gene set revealed by cluster analysis. For each of the 112 damage-induced genes, the fold change in expression level 4 h after NCS treatment was computed in uninfected cells and in the cells knocked-down for Rel-A, p53 and ATM, yielding a 112 × 4 data matrix, with the rows corresponding to genes.
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Abstract. Background: mRNA levels in cells are determined by the relative rates of RNA production and degradation. Yet, to date, most analyses of gene expression profiles were focused on mechanisms which regulate transcription, while the role of mRNA stability in modulating transcriptional networks was to a large extent overlooked.
We thank Gidi Weber and Adi Maron-Katz for their contributions to the source code. Promoter sequences were downloaded by Ran Elkon. We also thank the anonymous referees for their constructive comments. R.S. was supported in part by the Raymond and Beverly Sackler Chair in Bioinformatics and by a grant from the Wolfson Foundation.
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PAULETTE ELKON July 9, 1915 - October 8, 2019 . Sadly, on Tuesday, October 8, we had to say good-bye to our wonderful mom, grandma, aunt, and friend, Paulette. She was born on July 9, 1915 in Winnipeg's North End, the eldest of the three children of Gregory and Anna Matkosky. She attended Margaret Scott and Isaac Newton schools.
Korkmaz G, Lopes R, Ugalde AP, Nevedomskaya E, Han R, Myacheva K, Zwart W, Elkon R*, Agami R*. Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9. Nat Biotechnol. 2016, 34:192-8. (* Co-corresponding author) Friedman-Mazursky O, Elkon R, Efrat S. Redifferentiation of expanded human islet β cells by inhibition ...
BibTeX @MISC{Elkon_openaccess, author = {Ran Elkon and Jarno Drost and Gijs Van Haaften and Mathias Jenal and Mariette Schrier and Joachim Af and Oude Vrielink and Reuven Agami}, title = {Open Access E2F mediates enhanced alternative polyadenylation in proliferation}, year = {}}
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